Aistriú cothrománach géine
Is éard is aistriú cothrománach géine (ACG) nó aistriú cliathánach géine [1][2] ná an ghluaiseacht d'ábhar géiniteach idir orgánaigh aoncheallacha agus/nó ilcheallacha, cé is moite de tharchur ADN ó thuismitheoir chuig a shliocht.[3] Toisc thábhachtach is ea ACG in éabhlóid go leor orgánach.[4][5]
Tá ACG ina phríomh-mheicníocht i leathnú frithsheasmhacht in aghaidh antaibheathach i mbaictéir,[6][7][8][9] agus glacann sé ról tábhachtach in éabhlóid na mbaictéar gur féidir leo comhdhúile nuálacha, a leithéid agus lotnaidicídí shaorga a dhíghrádú[10] agus in éabhlóid, i gcothabháil, agus i dtarchur nimhneachta.[11] Is minic a bhíonn baictéarafagaigh mheasartha agus plasmaidí páirteach ann.[12][13][14] Is féidir le géinte, atá freagrach as frithsheasmhacht in aghaidh antaibheathach i speiceas baictéarach amháin, aistriú chuig speicis eile trí mheicníochtaí éagsúla, ar nós F pileas, agus ina dhiaidh sin faighteora na ngéinte frithsheasmhacht a armáil in aghaidh antaibheathach, a bhfuil ag éirí dúshlánach ó thaobh na sláinte de. Samhlaítear freisin go gcuireann ACG chun cinn cothabháil saol uilíoch na bithcheimice agus, ina dhiaidh sin, uilíocht an chóid ghéinitigh.[15] Bhí go leor machnaimh faoin ghéineolaíocht dírithe ar an aistriú cothrománach, ach níl an tábhacht a bhaineann le haistriú ingearach géine i measc orgánach aoncheallach ach ina thús.[16][17]
Is féidir glacadh le seachadadh géinte mar aistriú saorga géine, agus is saghas d' innealtóireacht ghéiniteach í.
Foinsí agus nótaí
cuir in eagar- ↑ Ochman, H., Lawrence, J. G., & Groisman, E. A. (May 2000). "Teideal in easnamh ar an lua Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}". Nature 405 (6784): 299–304. doi: . PMID 10830951.CS1 maint: Multiple names: authors list (link) Dunning Hotopp, J. C. (April 2011). "Teideal in easnamh ar an lua Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}". Trends in Genetics 27 (4): 157–163. doi: . PMID 21334091. PMC:3068243.
- ↑ Robinson, K. M., Sieber, K. B., & Dunning Hotopp, J. C. (October 2013). "A review of bacteria-animal lateral gene transfer may inform our understanding of diseases like cancer". PLoS Genet 9 (10): e1003877. doi: . PMID 24146634. PMC:3798261.CS1 maint: Multiple names: authors list (link)
- ↑ Keeling, P. J., & Palmer, J.D. (2008). "Teideal in easnamh ar an lua Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}". Nature Reviews Genetics 9 (8): 605–618. doi: . PMID 18591983.CS1 maint: Multiple names: authors list (link)
- ↑ Gyles, C. (March 2014). "Teideal in easnamh ar an lua Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}". Veterinary Pathology 51 (2): 328–340. doi: . PMID 24318976. Curtha i gcartlann 2016-08-12 ar an Wayback Machine
- ↑ "Speciation through the looking-glass" (2017). Biological Journal of the Linnean Society 120 (2): 480–488. doi: .
- ↑ OECD, Safety Assessment of Transgenic Organisms, Volume 4: OECD Consensus Documents, 2010, pp.171-174
- ↑ "In situ transfer of antibiotic resistance genes from transgenic (transplastomic) tobacco plants to bacteria" (July 2002). Appl. Environ. Microbiol. 68 (7): 3345–51. doi: . PMID 12089013. PMC:126776.
- ↑ "Teideal in easnamh ar an lua Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}" (2001). Annu. Rev. Microbiol. 55 (1): 709–42. doi: . PMID 11544372. PMC:4781227. Curtha i gcartlann 2019-09-19 ar an Wayback Machine
- ↑ Nielsen KM (1998). "{{{title}}}". APMIS Suppl. 84: 77–84. PMID 9850687.
- ↑ "Teideal in easnamh ar an lua Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}" (October 1998). Appl. Environ. Microbiol. 64 (10): 4089–92. PMID 9758850. PMC:106609.
- ↑ "Teideal in easnamh ar an lua Either specify one, or click here and a bot will try to complete the citation details for you. {{{title}}}" (December 2012). Frontiers in Cellular and Infection Microbiology 2. doi: . PMID 23248780.
- ↑ "Transfer of broad-host-range antibiotic resistance plasmids in soil microcosms" (1994). Curr. Microbiol. 28 (4): 209–215. doi: .
- ↑ "Efficient transfer of antibiotic resistance plasmids by transduction within methicillin-resistant Staphylococcus aureus USA300 clone" (2012). FEMS Microbiol. Lett. 332 (2): 146–152. doi:PMID 22553940. .
- ↑ "Molecular characterization of a new efficiently transducing bacteriophage identified in meticillin-resistant Staphylococcus aureus" (2016). Journal of General Virology 97 (1): 258–268. doi:PMID 26537974. .
- ↑ "On universal coding events in protein biogenesis" (2017). Biosystems. doi: .
- ↑ "Horizontal gene transfer in microbes much more frequent than previously thought".
- ↑ "To Share and Share Alike: Bacteria swap genes with their neighbors more frequently than researchers have realized".